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thiazole component of thiamine diphosphate biosynthesis I

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
[L-cysteine_desulfurase]-S-sulfanyl-L-cysteine + [ThiI_sulfur-carrier_protein]-L-cysteine <=> [L-cysteine_desulfurase]-L-cysteine + [ThiI_sulfur-carrier_protein]-S-sulfanyl-L-cysteine not assigned

S-adenosyl-L-methionine + L-tyrosine + NADPH <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + NADP+ + H+ 4.1.99.19 2-iminoacetate synthase

L-cysteine + [L-cysteine_desulfurase]-L-cysteine <=> L-alanine + [L-cysteine_desulfurase]-S-sulfanyl-L-cysteine not assigned

[ThiS] + ATP + H+ <=> adenylyl-[ThiS] + diphosphate 2.7.7.73 sulfur carrier protein ThiS adenylyltransferase

H+ + pyruvate + D-glyceraldehyde_3-phosphate <=> 1-deoxy-D-xylulose_5-phosphate + CO2 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase

1-deoxy-D-xylulose_5-phosphate + 2-iminoacetate + thiocarboxylated-[ThiS_sulfur-carrier_protein] <=> 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl_phosphate + H2O + [ThiS] 2.8.1.10 thiazole synthase

[ThiI_sulfur-carrier_protein]-S-sulfanyl-L-cysteine + adenylyl-[ThiS] + reduced_ferredoxin_[iron-sulfur]_cluster <=> thiocarboxylated-[ThiS_sulfur-carrier_protein] + [ThiI_sulfur-carrier_protein]-L-cysteine + AMP + oxidized_ferredoxin 2.8.1

Visualization of the pathway